1142: Association between vitamin D status and metabolic syndrome risk among Korean population: Based on the Korean National Health and Nutrition Examination Survey 2008-2010

J.Y. Kim, H.R. Lee
Family Medicine, GANGNAM SEVERANCE HOSPITAL, Seoul, Korea
Objective: Previous reports have shown that metabolic syndrome and some metabolic syndrome components are associated with serum 25-hydroxyvitamin D [25(OH)D]. We aimed to assess the association between the clinical range of vitamin D status (deficiency and insufficiency) and metabolic syndrome in the South Korean population.
Methods: In this cross-sectional study, we assessed 18,313 adults from the Korean National Health and Nutrition Examination Surveys (KNHANES), 2008–2010. Subjects were separately classified into 3 groups of serum 25(OH)D as deficiency(25(OH)DResults: The prevalence of vitamin D deficiency was 63.4% and insufficiency was 29.3%. Those in the insufficiency group of serum 25(OH)D had 23% higher odds [OR = 1.23; 95% confidence interval (CI) 1.07, 1.42] and deficiency group of serum 25(OH)D had 30% higher odds (OR = 1.30; 95% CI 1.13, 1.49) for metabolic syndrome as compared to those in the normal group. High homoeostasis model assessment of insulin resistance (HOMA-IR) (OR = 1.29; 95% CI 1.13, 1.47 for insufficiency group, OR = 1.54, 95% CI 1.36, 1.75 for deficiency group) were the main component associated with serum 25(OH)D. High blood pressure and hypertriglyceridaemia were also closely correlated components of metabolic syndrome according to serum 25(OH)D status.
Conclusions: We conclude that serum 25(OH)D deficiency and insufficiency are associated with elevated risk of metabolic syndrome.

Disclosure: No conflict of interest declared