499: Evolution of cardiovascular lifestyle behaviours and lipid parameters occurring concomitantly to the intake of phytosterol- supplemented yoghurt in hypercholesterolaemic patients treated with cholesterol-lowering drugs

E. Bruckert1, L. Massama2, O. Descampsc3, E. Bosi4, MJ Chapman1, FA Allaert5
1 Dpt cardiology, Hôpital Pitié Salpêtrière AP-HP, Paris, France; 2 Dpt cardiology, Saint Joan University,, Reus, Spain; 3 Centre de Recherche Médicale, Jolimont, Haine-Saint-Paul, Belgium
4 Cardiology dpt, Ospedale San Raffaele, Milano, Italy; 5 Chaire evaluation medicale, ESC et DIM CHU du Bocage, Dijon, France
Presentation type: Oral Communication
Objective: To assess changes in cardiovascular-related lifestyle behaviours associated with regular intake of a phytosterol-supplemented yogurt (Phyto-SY) in hypercholesterolaemic patients already treated with cholesterol-lowering drugs.
Methods: Two nationwide prospective observational studies involving 460 general practitioners in Spain and France have been pooled. Each GP recruited the 5 consecutive hypercholesterolaemic patients (taking or not cholesterol-lowering drugs) for whom they consider that lifestyle modifications and Phyto-SY was indicated. Study design included an inclusion visit, a patient’s self-monitoring assessment after 1 month and after 4 months. The main evaluation criterion was the change in the standardized Nutritional Lifestyle (NL) Score. Secondary criteria were changes in: Total, LDL and HDL cholesterol, waist circumference, and daily walking time. Results obtained in patients Currently Treated with cholesterol-lowering drugs (CTP) are presented in this abstract.
Results: The study included 1329 hypercholesterolaemic patients treated with cholesterol-lowering drugs (CTP), 58.6 years old ± 11.2 (women 53.9%). NL score decreased from 15.5 to 8.9 (p30 min) increased also significantly (pConclusion: Even in CTP, implementing consumption of Phyto-SY as part of a global healthy lifestyle advice leads to a nutritional improvement along with an improvement in lipid profile, anthropometry and physical activity.

Disclosure: No conflict of interest declared