746 Eurica: The Epidemiology Of Urinary Tract Infections (Uti) In Children With Acute Illness In Primary Care

O’Brien K, Butler C, Edwards A, Hood K
Kingdom obrienka@cardiff.ac.uk
Aims: The early diagnosis of Urinary Tract Infection (UTI) in children represents an important opportunity to alleviate acute morbidity and possibly prevent serious long-term complications. The diagnosis of UTI in young children is difficult, as they often present with non-specific features. One UK study found that 50% cases of UTI were missed in children. The reported rates of UTI among children vary greatly depending on setting and inclusion criteria. The prevalence of UTI in acutely ill children presenting in UK primary care is not known as no studies have systematically sampled urine from this population. Primary aim: Determine the prevalence of UTI in children under the age of five presenting in primary care with an acute illness. Secondary aims: Identify predictive values of symptoms, signs & urine dipsticks; explore the levels of a potential novel biomarker for UTI in urine; explore nature and resistance profile of uropathogenic organisms found.
Material and methods: Prospective cohort study of children under five years of age presenting with an acute illness (100,000 cfu/ml.
Results: Over 900 children were recruited from 13 practices across Wales and more than 600 urine samples obtained. The data is currently being cleaned and analysed.
Results will be available for presentation for the conference.
Conclusions: The findings of this research will help to inform the management of acutely ill children and help to determine which children should have their urine sampled when presenting in primary care.
EURICA: the epidemiology of urinary tract infections (UTI) in children with acute illness in primary care