Po1787 The Use Of Lactobacillus In The Prevention Of Bacterial Vaginosis Recurrence: Evidence Based Clinical Review

Conference: 
Author(s): 
Filipa Tavares1, Alexandrina Mendes2, Rui Oliveira3 e Cristina Sousa1
1USF Lidador; 2Maternidade Centro Hospitalardo Porto; 3USF Ponte, ACES do Alto Ave, Guimarães
Text: 
Introduction — Bacterial vaginosis (BV) is the most common cause of vaginal discharge in women of childbearing age, accounting for 40 to 50 percent of cases. Many patients have recurrence of infection in 3 to 12 months, no matter the treatment used.
Objective: To determine if the use of probiotics together with antibiotic treatment is effective in preventing recurrence of bacterial vaginosis.
Methods: A research of guidelines, systematic reviews, meta-analyses and randomized control trials was made, using Pubmed, evidence based medicine sites and bibliographic references used in the selected articles published between January the 1st 2009 and November the 30th 2013, in Portuguese and English, using the MeSH terms: bacterial vaginosis, probiotics and antibacterial agents. The Jadad scale was used to evaluate the methodological strength of the clinical trials and the Strength of Recommendation Taxonomy Scale of the American Family Physician (SORT) to evaluate the quality of the studies and establish the Strength of Recommendation.
Results: The search resulted in 363 articles of which only 3 met the inclusion criteria: a guideline, a systematic review and a clinical trial. The results do not provide sufficient evidence for or against recommending probiotics for the treatment of bacterial vaginosis. In addition, there is no conclusive evidence to recommend the use of probiotics either before during or after antibiotic treatment as a means of ensuring successful treatment or reduce recurrence.
Conclusion: The current search does not provide conclusive evidence for the use of probiotic preparations in conjunction with antibiotics for the prevention of bacterial vaginosis recurrence rate (SORT B). Larger, randomized controlled trials with standardized methodologies are needed to confirm the benefits of probiotics in the prevention of recurrence of bacterial vaginosis.
Literature: 
PO1787 THE USE OF LACTOBACILLUS IN THE PREVENTION OF BACTERIAL VAGINOSIS RECURRENCE: EVIDENCE BASED CLINICAL REVIEW
Keywords: 
bacterial vaginosis, probiotics and antibacterial agents