SERUM GLUCOSE LEVELS ON ADMISSION IN NON DIABETIC PATIENTS WITH ACUTE MYOCARDIAL INFRACTION REPRESENT AN INDEPENDENT PROGNOSTIC FACTOR OF THE FIRST YEAR MORTALITY

Author(s): 
I LENTZAS 1, A KAMARATOS 1, G BELOS 1, A MARIOLIS 1, A MELIDONIS 1
1Tzaneio General Hospital, Greece
Text: 
BACKGROUND/ AIM: It has been shown that serum glucose levels on admission constitute an independent risk factor in non-diabetic patients undergoing an acute coronary syndrome. The purpose of this study was to examine the possible relation between admission's serum glucose levels and the mortality rate during the first year follow-up of non-diabetic patients.
METHODS: prospective study of 848 and 666 patients with STEMI and NSTEMI respectively, admitted to the hospital during the first 12 hours after the onset of pain was carried out. Patients had no previous history of diabetes mellitus and serum glucose levels on admission was RESULTS: Overall mortality during the first year of follow up was 16.6% and 14.1 % for STEMI and NSTEMI, respectively. Year mortality of the group A, B and C STEMI patients was: 11.2%, 16.2%, and 20.4%, respectively (p=0.002), while for the NSTEMI patients was: 8%, 12.6% and 19.1%, respectively (p=0.002). In multifactor analysis serum glucose levels was found to be an independent mortality factor during the first year of follow up for both STEMI (p=0.007) and NSTEMI (pCONCLUSION: The results of the present study show that serum glucose levels on admission represent an independent factor of increased mortality during the first year of follow up in non diabetic patients with acute myocardial infraction with or without ST elevation.